Essential Oil of <i>Cymbopogon Citratus</i> Grown in Umuahia: A Viable Candidate for Anti-Inflammatory and Antioxidant Therapy

Abstract The essential oils of Cymbopogon citratus (EOCC) has found use in medicine, food and chemical industry. This study attempts to provide evidence its suitability for antioxidant anti-inflammatory therapy. Total phenol total flavonoid EOCC was 49.83±0.39mg GAE/g extract 352.82±3.45 µg QEC/g respectively. Gas chromatography-mass spectrometry (GC-MS) analysis oil showed 25 peaks with myrcenyl acetate (9.703%), caryophyllene (8.997%), citronella (6.383%) been the most abundant. vitro assay using human red blood cell (HRBC) membrane stabilization shows that at 200µg/mL, percentage inhibition significantly higher compared diclofenac both heat-induced hypotonic induced haemolysis. 2,2-diphenyl-1-picrylhydrazyl (DPPH) ferric reducing power (FRAP) assays a comparable dose-dependent increase from 50 400 ?g/mL relation vitamin C. Half maximal inhibitory concentration (IC50) (73.16±12.89 656.01±0.01 ?mol Fe (II)/L) remarkably C (69.09±4.52 246.79±0.01 DPPH FRAP In conclusion, results this establish preliminary on therapeutic potential managing inflammation oxidative stress caused by free radicals.